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Placenta Ingestion Enhances Analgesia Produced by Vaginal/Cervical Stimulation in Rats

Kristal, Dr. Mark B. and Thompson, Alexis C. and Heller, Steve B. and Komisaruk, Dr. Barry R. (1986) Placenta Ingestion Enhances Analgesia Produced by Vaginal/Cervical Stimulation in Rats. [Journal (Paginated)]

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Abstract

Ingestion of placenta has previously been shown to enhance opiate-mediated analgesia (measured as tail-flick latency) induced either by morphine injection or by footshock. The present study was designed to test whether placenta ingestion would enhance the partly opiate-mediated analgesia produced by vaginal/cervical stimulation. Nulliparous Sprague-Dawley rats were tested for analgesia, using tail-flick latency, during and after vaginal/cervical stimulation; the tests for vaginal/cervical stimulation-induced analgesia were administered both before and after the rats ate placenta or ground beef. Placenta ingestion, but not beef ingestion. significantly heightened vaginal/cervical stimulation-induced analgesia. A subsequent morphine injection provided evidence that, as in a previous report, placenta ingestion, but not beef ingestion, enhanced morphine-induced analgesia.

Item Type:Journal (Paginated)
Keywords:Placenta, Pain, Opiates, Vaginal stimulation-produced analgesia, Tail-flick test, Afterbirth, Analgesia, Parturition, Placentophagia, VSPA, Vaginal/cervical stimulation, POEF
Subjects:Biology > Behavioral Biology
Psychology > Psychobiology
Psychology > Physiological Psychology
Neuroscience > Behavioral Neuroscience
ID Code:6254
Deposited By:Kristal, Mark B.
Deposited On:02 Nov 2008 09:59
Last Modified:11 Mar 2011 08:57

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