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The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management

Raj, Satish R (2006) The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management. [Journal (Paginated)]

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Abstract

Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia, exercise intolerance, lightheadedness, extreme fatigue, headache and mental clouding. Patients with POTS demonstrate a heart rate increase of ≥30 bpm with prolonged standing (5-30 minutes), often have high levels of upright plasma norepinephrine (reflecting sympathetic nervous system activation), and many patients have a low blood volume. POTS can be associated with a high degree of functional disability. Therapies aimed at correcting the hypovolemia and the autonomic imbalance may help relieve the severity of the symptoms. This review outlines the present understanding of the pathophysiology, diagnosis, and management of POTS.

Item Type:Journal (Paginated)
Keywords:Postural Tachycardia Syndrome; Pathophysiology; Diagnosis; Management
Subjects:JOURNALS > Indian Pacing and Electrophysiology Journal
ID Code:4802
Deposited By:Indian Pacing and Electrophysiology, Journal
Deposited On:01 Apr 2006
Last Modified:12 Sep 2007 18:02

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