Effects of Endocardial Microwave Energy Ablation

Vicente, Climent and Aquilino, Hurlé and Siew Yen, Ho and Damián, Sánchez-Quintana (2005) Effects of Endocardial Microwave Energy Ablation. [Journal (Paginated)]

Full text available as:



Until recently the treatment of atrial fibrillation (AF) consisted primarily of palliation, mostly in the form of pharmacological intervention. However because of recent advances in nonpharmacologic therapies, the current expectation of patients and referring physicians is that AF will be cured, rather than palliated. In recent years there has been a rapid expansion in the availability and variety of energy sources and devices for ablation. One of these energies, microwave, has been applied clinically only in the last few years, and may be a promising technique that is potentially capable of treating a wide range of ventricular and supraventricular arrhythmias. The purpose of this study was to review microwave energy ablation in surgical treatment of AF with special interest in histology and ultrastructure of lesions produced by this endocardial ablation procedure.

Item Type:Journal (Paginated)
Keywords:atrial fibrillation; microwave ablation
Subjects:JOURNALS > Indian Pacing and Electrophysiology Journal
ID Code:4453
Deposited By:Indian Pacing and Electrophysiology, Journal
Deposited On:13 Jul 2005
Last Modified:11 Mar 2011 08:56

References in Article

Select the SEEK icon to attempt to find the referenced article. If it does not appear to be in cogprints you will be forwarded to the paracite service. Poorly formated references will probably not work.

1. Benjamin EJ, Wolf PA, D´Agostino RB, Silbershatz H, Kannel WB, Levy D. Impact of atrial fibrillation on the risk of death: The Framingham Heart Study. Circulation 1998; 98: 946-52.

2. Feinberg WM, Blackshear JL, Laupacis A, Kronmal R, Hart RG. Prevalence, age distribution, and gender of patients with atrial fibrillation: analysis and implications. Arch Intern Med. 1995;155:469-473.

3. Benjamin EJ, Levy D, Vaziri SM, D'Agostino RB, Belanger AJ, Wolf PA. Independent risk factors for atrial fibrillation in a population-based cohort: the Framingham Heart Study. JAMA. 1994;271:840–844.

4. Cox JL, Schuessler RB, Boineau JP. The surgical treatment of atrial fibrillation. I. Summary of the current concepts of mechanisms of atrial flutter and atrial fibrillation. J Thorac Cardiovasc Surg 1991; 101: 402-5.

5. Cox JL, Canavan TE, Schuessler RB, et al. The surgical treatment of atrial fibrillation. II. Intraoperative electrophysiologic mapping and description of the electrophysiologic basis of atrial flutter and atrial fibrillation. J Thorac Cardiovasc Surg 1991; 101: 406-26.

6. Cox JL, Schuessler RB, D´Agostino HJ, Stone CM, Chang BC, Cain ME. The surgical treatment of atrial fibrillation. III. Development of a definite surgical procedure. J Thorac Cardiovasc Surg 1991; 101: 569-83.

7. Cox JL. The surgical treatment of atrial fibrillation. IV. Surgical technique. J Thorac Cardiovasc Surg 1991; 101: 584-92.

8. Cox JL, Ad N, Palazzo T, et al. Current status of the maze procedure for the treatment of atrial fibrillation. Sem Thorac Cardiovasc Surg 2000; 12: 15-19.

9. McCarthy PM, Gillinov AM, Castle L, Chung M, Cosgrove D. The Cox-maze procedure: the Cleveland Clinic experience. Sem Thorac Cardiovasc Surg 2000; 12: 25-29.

10. Cox JL, Jaquiss RDB, Schuessler RB, Boineau JP. Modification of the maze procedure for atrial flutter and atrial fibrillation. II. Surgical technique of the maze III procedure. J Thorac Cardiovasc Surg 1995; 110: 485-95.

11. Haissaguerre M, Jais P, Shah DC, et al. Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Eng J Med 1998; 339: 659-66.

12. Morady F. Catheter ablation of supraventricular arrhythmias. PACE 2004; 27:125-42.

13. Oral H, Knight BP, Ozaydin M, et al. Mechanistic significance of intermittent pulmonary vein tachycardia in patients with atrial fibrillation. J Cardiovasc Electrophysiol 2002; 13: 645-50.

14. Allesie MA. Atrial fibrillation-induced electrical remodeling in humans: what is the next step?. Cardiovasc Res 1999; 44: 10-2.

15. Melo J, Adragao P, Neves J, et al. Surgery for atrial fibrillation: assessment of results at one year. Eur J Cardio-thorac Surg 1999; 15: 851-4.

16. Cox JL. The central controversy surrounding the interventional-surgical treatment of atrial fibrillation. J Thorac Cardiovasc Surg 2005; 129: 1-4.

17. Khargi K, Hutten BA, Lemke B, Deneke T. Surgical treatment of atrial fibrillation; a systematic review. Eur J Cardio-thorac Surg 2005; 27: 258-65.

18. Wang PJ, Homoud MK, Link MS, Estes III NA. Alternate energy sources for catheter ablation. Curr Cardiol Rep 1999;2:165-171.

19. Hurle A, Ibañez A, Parra JM, Martinez JG. Preliminary results with the microwave-modified maze III procedure for treatment of chronic atrial fibrillation. Pacing Clin Electrophysiol 2004;27:1644-1646.

20. Patwardhan AM, Dave HH, Tamhane AA, Pandit SP, Dalvi BV, Golam K, Kaul A, Chaukar AP. Intraoperative radiofrequency microbipolar coagulation to replace incisions of maze III procedure for correcting atrial fibrillation in patients with rheumatic valvular disease. Eur J Cardio-thorac Surg 1997; 12: 627-633.

21. Wisser W, Khazen C, Deviatko E, Stix G, Binder T, Seitelberger R, Schmidinger H and Wolner E: Microwave and radiofrequency ablation yield similar success rates for treatment of chronic atrial fibrillation. Eur J Cardio-thorac Surg 2004; 25: 1011-1017.

22. Whayne JG, Nath S, Haines DE. Microwave catheter ablation of myocardium in vitro. Assessment of the characteristics of tissue heating injury. Circulation 1994; 89: 2390-5.

23. Manasse E, Colombo PG, Barbone A, et al. Clinical histopathology and ultrastructural analysis of myocardium following microwave energy ablation. Eur J Cardio-thorac Surg 2003; 23: 573-7.

24. Climent V, Hurlé A, Ho SY, Sáenz-Santamaría J, Nogales AG, Sánchez-Quintana D. Early morphologic changes following microwave endocardial ablation for the treatment of chronic atrial fibrillation during mitral valve surgery. J Cardiovasc Electrophysiol 2004; 15: 1277-83.

25. Watanabe H, Hayashi J, Sugawara M,Hiratsuka M and Eguchi S:Experimental application of microwave tissue coagulation to ventricular myocardium. Ann Thorac Surg 1999; 67:666-671.

26. Keane D, Ruskin J, Norris N, Chapelon PA and Bérube D: In vitro and in vivo evaluation of the thermal patterns and lesions of catheter ablation with a microwave monole antenna. J Interv Card Electr 2004; 10:111-119.

27. Santiago T, Melo J, Gouveia RH, Neves J, Abecasis M, Adragão P and Martins AP: Epicardial radiofrequency applications: in vitro and in vivo studies on human atrial myocardium. Eur J Cardio-thorac Surg 2003; 24:481-486.

28. Fuller IA, Wood MA: Intramural coronary vasculature prevents transmural radiofrequency lesion formation. Circulation 2003; 107:1797-1803.

29. van Brakel TJ, Bolotin G, Salleng KJ, Nifong LW, Allesie MA, Chitwood WR, Maessen JG: Evaluation of Epicardial microwave ablation lesions: histology versus electrophysiology. Ann Thorac Surg 2004; 78:1397-1402.

30. Haugh C, Davidson ES, Mark Estes III NA, Wang P: Pulsing microwave energy: A method to create more uniform myocardial temperature gradients. J Interv Card Electr 1997;1:57-65.

31. Williams MR, Knaut M, Bèrubè D, Oz MC: Application of microwave energy in cardiac tissue ablation: From in vitro analyses to clinical use. Ann Thorac Surg 2002; 74:15001505.

32. Gillinov AM, Smedira NG, Cosgrove III DM: Microwave ablation of atrial fibrillation during mitral valve operations. Ann Thorac Surg 2002; 74:1259-1261.

33. Chiappini B, Di Bartolomeo R, Marinelli G: The surgical treatment of atrial fibrillation: preliminary experience and results. Interactive Cardiovascular and Thoracic Surgery 2003; 2:327-330.

34. Iwasa A, Storey J, Yao B, Liem LB, Feld GK: Efficacy of a microwave antenna for ablation of the tricuspid valve-inferior vena cava isthmus in dogs as a treatment for type 1 atrial flutter. J Interv Card Electr 2004; 10:191-198.

35. Ho SY, Anderson RH, Sanchez-Quintana D. Atrial structure and fibres: morphological basis of atrial conduction. Cardiovasc Res 2002;54:325-336.

36. Cabrera JA, Sanchez-Quintana D, Farre J, Rubio JA, Ho SY. The inferior right atrial isthmus: Further architectural insights for current and coming ablation technologies. J Cardiovasc Electrophysiol 2005;16:402-8.


Repository Staff Only: item control page