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Atrial Remodeling: Evolving Concepts

Biffi, Mauro and Boriani, Giuseppe (2003) Atrial Remodeling: Evolving Concepts. [Journal (Paginated)]

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Abstract

The term "Electrophysiological remodeling" defines the changes of atrial electrophysiologic properties taking place in atrial myocites during atrial fibrillation and/or following periods of sustained atrial fibrillation (AF). Early research was prompted by clinical observations: many patients were seen to get through increasingly frequent and longer paroxisms of AF to persistent AF, until chronic AF eventually ensued, without significant changes of underlying heart disease.

Item Type:Journal (Paginated)
Keywords:atrial remodeling
Subjects:JOURNALS > Indian Pacing and Electrophysiology Journal
ID Code:4288
Deposited By:Indian Pacing and Electrophysiology, Journal
Deposited On:02 May 2005
Last Modified:11 Mar 2011 08:56

References in Article

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1. Attuel P, et al. Failure in the rate adaptation of the atrial refractory periods: new parameter to assess atrial vulnerability. PACE 1984;7:1382.

2. Boutjdir M, et al. Inhomogeneity of cellular refractoriness in human atrium: factor or arrhythmia ? PACE 1986;9(II):1095-1100

3. Nattel S, et al. Electrophysiological remodeling: are ion channel static players or dynamic movers ? J Cardiovasc Electrophysiol 1999;10:1553-1556

4. Nattel S, et al. Atrial electrophysiological remodeling caused by rapid atrial activation: underlying mechanisms and clinical relevance to atrial fibrillation. Cardiovasc Res 1999;42:298-308

5. Van Wagoner, et al. Atrial L-type Ca++ currents and human atrial fibrillation. Circ Res 1999;85:428-436

6. Yue L, et al. Ionic remodeling underlying action potential changes in a canine model of atrial fibrillation. Circ Res 1997;81:512-525

7. Yue L, et al. Molecular mechanisms underlying ionic remodeling in a dog model of atrial fibrillation. Circ Res 1999;84:776-784

8. Wijffels MCEF, et al. Atrial fibrillation begets atrial fibrillation. Circulation 1995;92:1954-1968

9. Capucci A, et al. Dynamic electrophysiologic behavior of human atria during paroxysmal atrial fibrillation. Circulation 1995; 92: 1193 - 1202

10. Biffi M, et al. Electrophysiological effects of flecainide and propafenone on atrial fibrillation cycle and relationship with arrhythmia termination. Heart 1999;82:176-182

11. Biffi M, et al. Atrial fibrillation recurrence after internal cardioversion: prognostic importance of electrophysiologic parameters. Heart 2002; 87:443-448

12. Manios EG, et al. Changes in atrial electrical properties following cardioversion of chronic atrial fibrillation: relation with recurrence. Cardiovascular Research 2000;47:244-253

13. Tieleman RG, et al. Verapamil reduces tachycardia-induced electrical remodeling of the atria. Circulation 1997;95:1945-53

14. Goette A, et al. Electrical remodeling in atrial fibrillation: time course and mechanisms. Circulation 1996;94:2968-74

15. Daoud EG, et al. Effect of verapamil and procainamide on atrial fibrillation-induced electrical remodeling in humans. Circulation 1997;96:1542-1550

16. Tieleman RG, et al. Early recurrences of atrial fibrillation after electrical cardioversion: a result of fibrillation-induced electrical remodeling of the atria. J Am Coll Cardiol 1998;31:167-173

17. Lee SH, et al. Effect of verapamil on long term tachycardia-induced atrial electrical remodeling. Circulation 2000;101:200-206

18. Kumagai K, et al. Effects of verapamil on electrophysiological properties in paroxysmal atrial fibrillation. PACE 1993;16:309-316

19. Elvan A, et al. Pacing-induced chronic atrial fibrillation impairs sinus node function in dogs: electrphysiologic remodeling. Circulation 1996;94:2953-60

20. Gaspo R, et al. Functional mechanisms underlying tachycardia-induced sustained atrial fibrillation in a chronic dog model. Circulation 1997;96:4027-35

21. Morillo CA, et al. Chronic rapid atrial pacing: structural, functional, and electrophysiological characteristics of a new model of sustained atrial fibrillation. Circulation 1995;91:1588-95

22. Fareh S, et al. The T-type Ca2+ channel blocker mibefradil prevents the development of a substrate for atrial fibrillation by tachycardia-induced atrial remodeling in dogs. Circulation 1999;100:2191-97

23. Fareh S, et al. Differential efficacy of L- and T-type calcium channel blockers in preventing tachycardia-induced remodeling in dogs. Cardiovasc Res 2001;49:762-770

24. Kannel WB et al. Epidemiologic features of atrial fibrillation: the Framingham study. N Engl J Med 1982;306:1018-22

25. Hasenfuss G. Alterations of calcium-regulatory proteins in heart failure. Cardiovasc Res 1998;37:279-289

26. Flesch M, et al. Evidence for a functional relevance of an enhanced expression of the Na+-Ca++ exchanger in failing human myocardium. Circulation 1996;94:992-1002

27. Pogwizd SM, et al. Upregulation of Na+/Ca++ exchanger expression and function in an arrhythmogenic rabbit model of heart failure Circ Res 1999;85:1009-1019

28. Hobai IA, et al. Enhanced Ca++-activated Na+-Ca++ exchange activity in canine pacing-induced herat failure Circ Res 2000;87:690-698

29. Pogwizd SM, et al. Arrhythmogenesis and contractile dysfunction in heart failure: roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness. Circ Res 2001;88:1159-67

30. Danshi Li, et al. Effects of experimental heart failure on atrial cellular and ionic electrophysiology. Circulation 2000;101:2631-38

31. Danshi Li, et al Contrasting efficacy of dofetilide in differing experimental models of atrial fibrillation. Circulation 2000;102:104-112

32. Torp-Pedersen C, et al. Dofetilide in patients with congestive heart failure and left ventricular dysfunction. N Engl J Med 1999;341:857-865

33. Shinigawa K, et al. Dynamic nature of atrial fibrillation substrate during development and reversal of heart failure in dogs. Circulation 2002;105:2672-78

34.. Danshi Li, et al. Effects of angiotensin-converting enzyme inhibition on the development of the atrial fibrillation substrate in dogs with ventricular tachypacing-induced congestive heart failure. Circulation 2001104:2608-14

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