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Preventing Sudden Death And The Use Of Prophylactic Implanted Defibrillators

Ray, Indranill Basu (2003) Preventing Sudden Death And The Use Of Prophylactic Implanted Defibrillators. [Journal (Paginated)]

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Abstract

Implanted defibrillators have become mainstream therapy for the prevention of sudden cardiac death from ventricular tachyarrhythmias. A decade of studies has confirmed the superiority of ICDs over antiarrhythmic drug therapy in prolonging the life of patients with a prior history of sustained VT or VF. More recent studies have compared ICD therapy to drugs or no antiarrhythmic therapy as ‘primary prophylaxis’ in patients considered at high risk for sudden death or with prior MIs. In selected patients, ICDs lead to important relative and absolute reductions in mortality in patients with no prior history of sustained VT or VF. Clinicians need to carefully consider these studies in their management of patients with CAD and severe LV dysfunction.

Item Type:Journal (Paginated)
Keywords:sudden cardiac death; Implanted Defibrillators
Subjects:JOURNALS > Indian Pacing and Electrophysiology Journal
ID Code:4285
Deposited By:Indian Pacing and Electrophysiology, Journal
Deposited On:02 May 2005
Last Modified:11 Mar 2011 08:56

References in Article

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1. Hauer RN, Aliot E, Block M, Capucci A, Luderitz B, Santini M, Vardas PE. Indications for implantable cardioverter defibrillator (ICD) therapy. Study Group on Guidelines on ICDs of the Working Group on Arrhythmias and the Working Group on Cardiac Pacing of the European Society of Cardiology. Eur Heart J. 2001 Jul;22(13):1074-81.

2. Julian DG, Camm AJ, Frangin G, et al. Randomized trial of effect of amiodarone on mortality in patients with left ventricular dysfunction after recent myocardial infarction: EMIAT. Lancet 1997; 349:667-74.

3. Deedwania PC, Singh BN, Ellenbogen K, et al. for the Department of Veterans Affairs CHF-STAT Investigators. Spontaneous conversion and maintenance of sinus rhythm by amiodarone in patients with heart failure and atrial fibrillation. Circulation 1998; 98:2574-2579.

4. Cairns JA, Connolly SJ, Roberts R, et al. for the Canadian Myocardial Infarction Arrhythmia Trial Investigators. Randomized trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarizations: CAMIAT. Lancet 1997; 349:675-82.

5. Kober L, Bloch Thomsen PE, Moller M, et al. Danish Investigators of Arrhythmia and Mortality on Dofetilide (DIAMOND) Study Group. Effect of dofetilide in patients with recent myocardial infarction and left-ventricular dysfunction: a randomized trial. Lancet 2000; 356:2052-8.

6. Moller M, Torp-Pedersen CT, Kober L. Dofetilide in patients with congestive heart failure and left ventricular dysfunction: safety aspects and effect on atrial fibrillation. The Danish Investigators of Arrhythmia and Mortality on Dofetilide (DIAMOND) Study Group. Congest Heart Fail. 2001;7(3):146-150.

7. Camm AJ, Pratt CM, Schwartz PJ, Al-Khalidi HR, Spyt M, Holroyde MJ, Karam R, Sonnenblick EH, Brum JM. Azimilide Post Infarct Survival Evaluation (ALIVE): Azimilide does not affect mortality in post-myocardial infarct patients. (abst) Circulation 2001;104(25):1B.

8. The Antiarrhythmics Vs Implantable Defibrillator (AVID) Investigators. A comparison of antiarrhythmic drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias. N Engl J Med 1997; 337:1576-83.

9. Connolly SJ, Gent M, Roberts RS, et al. Canadian Implantable Defibrillator Study (CIDS): a randomized trial of the implantable cardioverter defibrillator against amiodarone. Circulation 2000; 101:1297-302.

10. Kuck KH, Cappato R, Siebels J, Rüppel. Randomized comparison of antiarrhythmic drug therapy with implantable defibrillators in patients resuscitated from cardiac arrest : the Cardiac Arrest Study Hamburg (CASH). Circulation. 2000;102(7):748-54.

11. Connolly SJ, Hallstrom AP, Cappato R, Schron EB, Kuck KH, Zipes DP, Greene HL, Boczor S, Domanski M, Follman D, Gent M, Roberts RS. Meta-analysis of the implantable cardioverter defibrillator secondary prevention trials. AVID, CASH and CIDS studies. Antiarrhythmics vs Implantable Defibrillator study. Cardiac Arrest Study Hamburg . Canadian Implantable Defibrillator Study. Eur Heart J. 2000;21(24):2071-8.

12. Sheldon R, O'Brien BJ, Blackhouse G, Goeree R, Mitchell B, Klein G, Roberts RS, Gent M, Connolly SJ. Effect of clinical risk stratification on cost-effectiveness of the implantable cardioverter-defibrillator: the Canadian implantable defibrillator study. Circulation. 2001;104(14):1622-6.

13. Moss AJ, Hall WJ, Cannom DS, Daubert JP, Higgins SL, Klein H, Levine JH, Saksena S, Waldo AL, Wilber D, Brown MW, Heo M. Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia. Multicenter Automatic Defibrillator Implantation Trial Investigators. N Engl J Med. 1996;335(26):1933-40.

14. Bigger JT. Prophylactic use of implanted cardiac defibrillators in patients at high risk for ventricular arrhythmias after coronary-artery bypass graft surgery. Coronary Artery Bypass Graft (CABG) Patch Trial Investigators. N Engl J Med. 1997;337(22):1569-75.

15. Buxton, A.E., et al., A randomized study of the prevention of sudden death in patients with coronary artery disease. Multicenter UnSustained Tachycardia Trial Investigators. N Engl J Med, 1999;341(25):1882-90.

16. Gregoratos,G et al ACC/AHA/NASPE 2002 Guideline for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices. Available at http://www.acc.org/clinical/guidelines/pacemaker/pacemaker.pdf.

17. Moss AJ, Zareba W, Hall WJ, Klein H, Wilber DJ, Cannom DS, Daubert JP, Higgins SL, Brown MW, Andrews ML. Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N Engl J Med. 2002;346(12):877-83.

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